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2-Amino-1-Boc-imidazole

  • CAS No. 929568-19-4

  • Cat. No. CS-0130473
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Amino-1-Boc-imidazole|CS-0130473

Structure of 929568-19-4

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General Information

  • CAS No. 929568-19-4
  • Cat. No. CS-0130473
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₃N₃O₂
  • Molecular Weight 183.21
  • Synonym(s) tert-butyl 2-amino-1H-imidazole-1-carboxylate
  • SMILES O=C(OC(C)(C)C)N1C=CN=C1N

Description

2-Amino-1-Boc-imidazole serves as a protected imidazole scaffold for synthetic applications, offering enhanced stability and compatibility in multi-step organic transformations. The Boc group enables selective deprotection under mild acidic conditions, facilitating downstream functionalization. This derivative integrates efficiently into heterocyclic frameworks requiring nitrogen-rich, electron-donating moieties with controlled reactivity.

Application

2-Amino-1-Boc-imidazole serves as a versatile building block in medicinal chemistry, enabling efficient access to imidazole-containing scaffolds. The Boc group provides stability and ease of removal under mild acidic conditions, while the amino functionality supports diverse transformations including alkylation, acylation, and coupling reactions. Its compatibility with standard peptide and heterocyclic synthesis protocols makes it a practical choice for constructing bioactive molecules and functional intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   70.14
  • LogP   1.2485
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   0

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