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CS-W001157 4
Total: USD 88.00

2-Methyl-6-pyridinylacetic acid

  • CAS No. 92917-49-2

  • Cat. No. CS-W021724
  • Purity≥97%
  • MDL No.MFCD09924895

*For research and further manufacturing use only, not for direct human use.

2-Methyl-6-pyridinylacetic acid|CS-W021724

Structure of 92917-49-2

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General Information

  • CAS No. 92917-49-2
  • Cat. No. CS-W021724
  • Purity ≥97%
  • MDL No. MFCD09924895
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₂
  • Molecular Weight 151.16
  • Synonym(s) 2-(6-Methylpyridin-2-yl)acetic acid
  • SMILES O=C(O)CC1=CC=CC(C)=N1

Description

2-Methyl-6-pyridinylacetic acid features a pyridine ring substituted with a methyl group at the 2-position and a carboxylic acid-bearing acetyl side chain at the 6-position. This configuration imparts enhanced solubility and metabolic stability, enabling its use in bioactive molecule synthesis. The compound serves as a key scaffold for pharmaceutical intermediates requiring electron-deficient heteroaromatic systems.

Application

2-Methyl-6-pyridinylacetic acid serves as a versatile building block for medicinal chemistry and agrochemical synthesis, enabling efficient construction of bioactive heterocyclic scaffolds. Its pyridine core provides enhanced solubility and metabolic stability, while the carboxylic acid functionality facilitates direct coupling reactions or derivatization via standard amide, ester, or acyl transfer protocols. The methyl group at the 2-position enhances steric control in downstream transformations, contributing to predictable regioselectivity in functionalization processes. This compound exhibits excellent bench stability and is compatible with common purification methods, making it well-suited for scalable synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.01712
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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