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CS-W001157 4
Total: USD 88.00

4,6-Dibromoquinoline

  • CAS No. 927801-13-6

  • Cat. No. CS-0155640
  • Purity≥98%
  • MDL No.MFCD08436999

*For research and further manufacturing use only, not for direct human use.

4,6-Dibromoquinoline|CS-0155640

Structure of 927801-13-6

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General Information

  • CAS No. 927801-13-6
  • Cat. No. CS-0155640
  • Purity ≥98%
  • MDL No. MFCD08436999
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₅Br₂N
  • Molecular Weight 286.95
  • Synonym(s) 4,6-dibromo-quinoline
  • SMILES C1=CC2=NC=CC(=C2C=C1Br)Br

Description

4,6-Dibromoquinoline is a brominated quinoline derivative featuring two bromine atoms at the 4 and 6 positions, enabling selective cross-coupling reactions. This electron-deficient heterocycle integrates readily into complex molecular architectures, offering enhanced reactivity in palladium-catalyzed transformations. Its bench-stable nature supports reliable handling under standard conditions.

Application

4,6-Dibromoquinoline serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined regiochemistry and stable bromine substituents. The molecule exhibits excellent bench stability and facilitates the construction of complex heterocyclic scaffolds through sequential functionalization. Its orthogonal reactivity profile supports the synthesis of biaryl systems and advanced pharmaceutical intermediates with predictable outcomes in standard coupling protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.7598
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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