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CS-W001157 4
Total: USD 88.00

5-Bromoquinoline

  • CAS No. 4964-71-0

  • Cat. No. CS-W002559
  • Purity≥97%
  • MDL No.MFCD00234481

*For research and further manufacturing use only, not for direct human use.

5-Bromoquinoline|CS-W002559

Structure of 4964-71-0

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General Information

  • CAS No. 4964-71-0
  • Cat. No. CS-W002559
  • Purity ≥97%
  • MDL No. MFCD00234481
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆BrN
  • Molecular Weight 208.06
  • Synonym(s) None
  • SMILES BrC1=C2C=CC=NC2=CC=C1

Description

5-Bromoquinoline is a heterocyclic compound featuring a bromine atom at the 5-position of the quinoline core. This electron-deficient scaffold serves as a key building block in medicinal chemistry and materials science, enabling efficient coupling reactions via palladium catalysis. The bromine substituent facilitates functionalization while maintaining structural stability under standard conditions.

Application

5-Bromoquinoline serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. Its bromine substituent provides high reactivity under standard conditions while maintaining bench stability and compatibility with diverse functional groups. The quinoline core offers inherent utility in constructing biologically relevant scaffolds, particularly in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.9973
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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