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Structure of 926241-24-9
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This trifluoromethyl-substituted pyrazole acetic acid integrates a polar carboxylate handle with enhanced electron-withdrawing character from the trifluoromethyl group, enabling efficient conjugation and solubility in aqueous-organic mixtures.
2-[3-(Trifluoromethyl)-1H-pyrazol-1-yl]acetic acid serves as a versatile building block for medicinal chemistry, enabling the introduction of a polar, electron-deficient trifluoromethylpyrazole moiety adjacent to a carboxylic acid. The molecule exhibits bench stability and facilitates direct coupling reactions, including amide formation and esterification, with high functional group tolerance. Its utility is well-established in constructing bioactive scaffolds, particularly in kinase inhibitor and CNS-targeted compound development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: