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CS-W001157 4
Total: USD 88.00

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-2-cyclohexylacetic acid

  • CAS No. 925240-97-7

  • Cat. No. CS-0058684
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-2-cyclohexylacetic acid|CS-0058684

Structure of 925240-97-7

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General Information

  • CAS No. 925240-97-7
  • Cat. No. CS-0058684
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₂₇NO₄
  • Molecular Weight 393.48
  • Synonym(s) (S)-a-[Fmoc-(methyl)amino]cyclohexaneacetic acid
  • SMILES O=C(N(C)[C@H](C(O)=O)C1CCCCC1)OCC2C3=C(C=CC=C3)C4=C2C=CC=C4

Description

This fluoren-9-ylmethoxycarbonyl-protected amino acid derivative features a chiral cyclohexyl-substituted acetic acid backbone, enabling direct incorporation into peptide synthesis workflows. The robust Fmoc group ensures orthogonal protection, while the sterically defined (S)-configuration supports high diastereoselectivity in coupling reactions. This bench-stable reagent facilitates efficient N-terminal anchoring of complex peptide sequences under standard conditions.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-2-cyclohexylacetic acid serves as a robust chiral building block for peptide and non-peptidic scaffold synthesis. The Fmoc-methylamino group enables efficient N-terminal protection with orthogonal deprotection, while the cyclohexyl-substituted α-carbon provides steric definition and enhanced metabolic stability. Its bench-stable, crystalline nature facilitates straightforward purification and compatibility with standard coupling protocols in solid-phase and solution-phase workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   4.9008
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

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