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Structure of 924646-90-2
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2-Bromo-5-(difluoromethyl)thiophene features a difluoromethyl group that imparts enhanced metabolic stability and lipophilicity, making it valuable for medicinal chemistry applications. The bromine substituent enables facile cross-coupling reactions, while the thiophene core provides a rigid, electron-deficient platform for building complex heterocyclic architectures under standard conditions.
2-Bromo-5-(difluoromethyl)thiophene serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions with high functional group tolerance. The difluoromethyl group imparts enhanced metabolic stability and modulates electronic properties, while the bromo substituent facilitates efficient C–C bond formation. Its bench-stable, crystalline nature simplifies handling and purification in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H302-H312-H315-H319-H332-H335
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: