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CS-W001157 4
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1-(4-Hydroxy-3,5-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol

  • CAS No. 92409-34-2

  • Cat. No. CS-0161916
  • Purity≥97%
  • MDL No.MFCD29047019

*For research and further manufacturing use only, not for direct human use.

1-(4-Hydroxy-3,5-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol|CS-0161916

Structure of 92409-34-2

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General Information

  • CAS No. 92409-34-2
  • Cat. No. CS-0161916
  • Purity ≥97%
  • MDL No. MFCD29047019
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₂O₇
  • Molecular Weight 350.36
  • Synonym(s) None
  • SMILES OC(C1=CC(OC)=C(O)C(OC)=C1)C(OC2=CC=CC=C2OC)CO

Description

This triol integrates a hydroxyphenyl moiety with two methoxy groups and a 2-methoxyphenoxy linkage, offering enhanced solubility and stability under standard conditions. The para-hydroxyl group enables efficient coupling reactions, while the ortho-methoxy substitution minimizes undesired side reactivity.

Application

1-(4-Hydroxy-3,5-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol serves as a versatile polyfunctional building block for the synthesis of bioactive heterocycles and natural product analogs. Its multiple phenolic hydroxyls and ether linkages enable facile derivatization via esterification, glycosylation, or Suzuki coupling. Bench-stable and amenable to purification by flash chromatography, it functions as a key scaffold in medicinal chemistry campaigns targeting antioxidant and neuroprotective agents.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   97.61
  • LogP   1.8913
  • H_Acceptors   7
  • H_Donors   3
  • Rotatable_Bonds   8

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