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CS-W001157 4
Total: USD 88.00

4-Bromoisoindoline hydrochloride

  • CAS No. 923590-95-8

  • Cat. No. CS-W007793
  • Purity≥97%
  • MDL No.MFCD10700134
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Bromoisoindoline hydrochloride|CS-W007793

Structure of 923590-95-8

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Description

4-Bromoisoindoline hydrochloride offers a stable, moisture-tolerant platform for constructing complex heterocycles in synthetic organic chemistry. This bench-stable derivative features a brominated isoindoline core that integrates readily into cross-coupling reactions and enables direct functionalization at the 4-position. Its crystalline form simplifies handling and purification in process development workflows.

Application

4-Bromoisoindoline hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to isoindoline-based scaffolds prevalent in bioactive molecules. Its bench-stable form facilitates handling and purification, while the bromine substituent supports diverse cross-coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig couplings. Functions effectively in the synthesis of pharmaceutical intermediates and functionalized heterocycles under standard reaction conditions.

General Information

  • CAS No. 923590-95-8
  • Cat. No. CS-W007793
  • Purity ≥97%
  • MDL No. MFCD10700134
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BrClN
  • Molecular Weight 234.52
  • Synonym(s) 4-Bromo-Isoindoline Hcl
  • SMILES BrC1=CC=CC2=C1CNC2.Cl

Computational Chemistry Data

  • TPSA   12.03
  • LogP   2.4741
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335-H411
Precautionary Statements : P261-P264-P271-P273-P280-P302+P352-P304+P340-P362+P364-P391-P405-P501

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