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CS-W001157 4
Total: USD 88.00

2,2-Difluorocyclohexanamine hydrochloride

  • CAS No. 921602-83-7

  • Cat. No. CS-W021472
  • Molecule weight171.62
  • Purity≥97%
  • MDL No.MFCD11878024

*For research and further manufacturing use only, not for direct human use.

2,2-Difluorocyclohexanamine hydrochloride|CS-W021472

Structure of 921602-83-7

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General Information

  • CAS No. 921602-83-7
  • Cat. No. CS-W021472
  • Purity ≥97%
  • MDL No. MFCD11878024
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClF₂N
  • Molecular Weight 171.62
  • Synonym(s) 2,2-Difluorocyclohexan-1-aMine hydrochloride
  • SMILES Cl.NC1CCCCC1(F)F

Description

2,2-Difluorocyclohexanamine hydrochloride delivers a rigid, electron-deficient cyclohexane scaffold with enhanced metabolic stability. The difluoro substitution at the geminal position imparts unique conformational restraint and polarity, while the hydrochloride salt ensures excellent solubility and handling convenience in synthetic workflows.

Application

2,2-Difluorocyclohexanamine hydrochloride serves as a valuable building block in medicinal chemistry, offering enhanced metabolic stability and modulated lipophilicity due to the geminal difluoro substitution. The amine functionality enables straightforward derivatization via amidation, alkylation, or reductive amination, while the hydrochloride salt ensures excellent solubility and bench stability for routine synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.9448
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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