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Structure of 92053-25-3
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This chiral building block features a stereogenic center at the propan-2-ol carbon, bearing a pyrrolidin-2-yl group that enhances solubility and enables hydrogen bonding. The tertiary alcohol functionality offers stability under standard conditions, while the pyrrolidine moiety provides a nitrogen-rich site for further derivatization in medicinal chemistry applications.
(S)-2-(Pyrrolidin-2-yl)propan-2-ol serves as a valuable chiral building block in medicinal chemistry, leveraging its tertiary alcohol functionality and stereogenic center for asymmetric synthesis. The pyrrolidine moiety provides a polar, basic nitrogen that facilitates hydrogen bonding and enhances solubility, while the tert-butyl-like steric bulk improves metabolic stability. It functions effectively in nucleophilic substitution and coupling reactions, offering excellent bench stability and ease of purification—making it well-suited for late-stage functionalization in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: