Lot numbers can be found on the outside label of a product:
Methyl 2-(5-bromopyridin-2-yl)acetate
-
CAS No. 917023-06-4
- Cat. No. CS-0036244
- Purity≥98%
- MDL No.MFCD12031821
*For research and further manufacturing use only, not for direct human use.
Structure of 917023-06-4
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 917023-06-4
- Cat. No. CS-0036244
- Purity ≥98%
- MDL No. MFCD12031821
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₈BrNO₂
- Molecular Weight 230.06
- Synonym(s) (5-bromo-2-pyridinyl)-acetic acid methyl ester
- SMILES COC(=O)CC1=NC=C(C=C1)Br
Description
Methyl 2-(5-bromopyridin-2-yl)acetate features a brominated pyridine ring linked to a methyl acetate group, enabling direct incorporation into cross-coupling reactions. The electron-deficient pyridine moiety enhances reactivity in palladium-catalyzed transformations, while the ester functionality offers synthetic versatility for downstream derivatization. This bench-stable compound serves as a key building block for pharmaceutical intermediates and functional materials.
Application
Methyl 2-(5-bromopyridin-2-yl)acetate serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation in the synthesis of biologically active heterocycles. The bromopyridine moiety facilitates Suzuki, Stille, and Negishi couplings, while the ester group offers compatibility with reduction and functionalization protocols. Its bench-stable nature and straightforward purification make it ideal for iterative synthetic sequences in medicinal chemistry and process development.
Synthesis
-
Route1
-
192642-83-4 -
18107-18-1
- ~69%
-
In-stock
917023-06-4
References
-
CHUGAI SEIYAKU KABUSHIKI KAISHA Patent: EP1894911 A1, 2008 ; Location in patent: Page/Page column 82 ;
-
-
Route2
-
67-56-1
-
In-stock
192642-85-6 - ~92%
-
In-stock
917023-06-4
References
-
Liang, Chungen; Tang, Guozhi; Wong, Jason Christopher; Wu, Xihan Patent: US2010/69328 A1, 2010 ; Location in patent: Page/Page column 36 ;
-
-
Route3
-
In-stock
3430-13-5 - ~%
-
In-stock
917023-06-4
References
-
AFRAXIS, INC.; CAMPBELL, David; DURÓN, Sergio, G. Patent: WO2013/43232 A2, 2013 ; WO 2013/043232 A2
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 39.19
- LogP 1.5596
- H_Acceptors 3
- H_Donors 0
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Methyl 2-(5-bromopyridin-2-yl)acetate sigmaMethyl 2-(5-bromopyridin-2-yl)acetate manufacturerMethyl 2-(5-bromopyridin-2-yl)acetate priceMethyl 2-(5-bromopyridin-2-yl)acetate structureMethyl 2-(5-bromopyridin-2-yl)acetate SDSbuy Methyl 2-(5-bromopyridin-2-yl)acetateMethyl 2-(5-bromopyridin-2-yl)acetate supplierMethyl 2-(5-bromopyridin-2-yl)acetate usesMethyl 2-(5-bromopyridin-2-yl)acetate molecular weightprice of Methyl 2-(5-bromopyridin-2-yl)acetateMethyl 2-(5-bromopyridin-2-yl)acetate chemical name formula of Methyl 2-(5-bromopyridin-2-yl)acetate