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CS-W001157 4
Total: USD 88.00

2-Bromo-8-iodo-dibenzofuran

  • CAS No. 916435-41-1

  • Cat. No. CS-0168411
  • Molecule weight372.98
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Bromo-8-iodo-dibenzofuran|CS-0168411

Structure of 916435-41-1

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General Information

  • CAS No. 916435-41-1
  • Cat. No. CS-0168411
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₆BrIO
  • Molecular Weight 372.98
  • Synonym(s) 2-bromo-8-iododibenzo[b,d]furan
  • SMILES IC1=CC=C(OC2=CC=C(Br)C=C23)C3=C1

Description

2-Bromo-8-iodo-dibenzofuran features a dibenzofuran scaffold bearing bromine and iodine substituents at the 2- and 8-positions, respectively. This configuration enables selective cross-coupling reactions in transition-metal catalysis, leveraging the orthogonal reactivity of halogens. The molecule exhibits enhanced stability under standard conditions and serves as a key intermediate in the synthesis of complex heterocyclic architectures for materials science and medicinal chemistry applications.

Application

2-Bromo-8-iodo-dibenzofuran serves as a versatile bifunctional building block for palladium-catalyzed cross-coupling reactions. The bromo and iodo substituents enable sequential or orthogonal coupling, facilitating the construction of complex biaryl architectures. Its stability under standard reaction conditions and compatibility with diverse functional groups make it well-suited for applications in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   13.14
  • LogP   4.9531
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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