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Structure of 915412-18-9
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1-Bromo-3-iodo-5-methoxybenzene features complementary halogen handles enabling sequential cross-coupling in late-stage functionalization. The electron-donating methoxy group enhances reactivity in palladium-catalyzed processes, while the orthogonal bromo and iodo substituents allow selective transformation sequences. This aryl dihalide delivers precise molecular diversification under standard conditions.
1-Bromo-3-iodo-5-methoxybenzene serves as a versatile dihalogenated aromatic building block for palladium-catalyzed cross-coupling reactions. The bromo and iodo substituents enable sequential functionalization via Suzuki, Stille, or Negishi couplings, while the methoxy group provides moderate electron donation and orthogonality in multi-step synthesis. Its bench-stable nature and compatibility with standard reaction conditions make it suitable for constructing complex arenes and heterocyclic scaffolds in medicinal chemistry and materials science workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: