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Structure of 914637-07-3
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2-Bromo-3-(trifluoromethyl)benzonitrile features a trifluoromethyl group flanking a nitrile and bromine substituents on a benzene ring, enabling direct functionalization in cross-coupling reactions. This electron-deficient aryl halide integrates readily into complex molecular architectures under palladium catalysis, offering high stability and predictable reactivity in synthetic workflows.
2-Bromo-3-(trifluoromethyl)benzonitrile serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its reactive bromo group and electron-withdrawing trifluoromethyl and nitrile functionalities. The molecule exhibits good bench stability and facilitates efficient functionalization under standard Suzuki, Stille, or Negishi conditions, with the nitrile group offering additional handles for downstream derivatization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: