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Structure of 29848-59-7
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1-Bromo-3-(difluoromethyl)benzene features a strategically positioned difluoromethyl group that imparts enhanced lipophilicity and metabolic stability. This electron-deficient aryl bromide integrates readily into cross-coupling reactions, enabling efficient construction of fluorinated aromatic architectures under standard conditions.
1-Bromo-3-(difluoromethyl)benzene serves as a versatile building block for the synthesis of fluorinated aromatic compounds. The bromine moiety enables palladium-catalyzed cross-coupling reactions, while the difluoromethyl group provides enhanced metabolic stability and modulates electronic properties. This compound exhibits good bench stability and compatibility with standard functional group transformations, facilitating efficient access to complex fluorinated scaffolds in medicinal chemistry and agrochemical research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: