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CS-W001157 4
Total: USD 88.00

(6-Chloro-2-methylpyridin-3-yl)boronic acid

  • CAS No. 913836-15-4

  • Cat. No. CS-W017650
  • Purity≥97%
  • MDL No.MFCD07368875

*For research and further manufacturing use only, not for direct human use.

(6-Chloro-2-methylpyridin-3-yl)boronic acid|CS-W017650

Structure of 913836-15-4

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General Information

  • CAS No. 913836-15-4
  • Cat. No. CS-W017650
  • Purity ≥97%
  • MDL No. MFCD07368875
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BClNO₂
  • Molecular Weight 171.39
  • Synonym(s) 6-Chloro-2-methylpyridine-3-boronic acid
  • SMILES CC1=NC(Cl)=CC=C1B(O)O

Description

This boronate moiety features a chlorine-substituted pyridine core, enabling efficient coupling in Suzuki-Miyaura reactions. The methyl group enhances regioselectivity and stability under standard conditions, while the boronic acid functionality offers reliable reactivity and bench-stable handling for synthetic applications.

Application

(6-Chloro-2-methylpyridin-3-yl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. The ortho-chloro substituent provides a handle for downstream functionalization via nucleophilic substitution or further coupling, while the boronic acid group offers excellent bench stability and compatibility with standard Suzuki-Miyaura conditions. Its defined regiochemistry and predictable reactivity make it a reliable scaffold for medicinal chemistry and materials synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   -0.27678
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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