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CS-W001157 4
Total: USD 88.00

(2-Chloro-5-ethoxyphenyl)boronic acid

  • CAS No. 913835-30-0

  • Cat. No. CS-0151482
  • Purity≥97%
  • MDL No.MFCD08235081

*For research and further manufacturing use only, not for direct human use.

(2-Chloro-5-ethoxyphenyl)boronic acid|CS-0151482

Structure of 913835-30-0

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General Information

  • CAS No. 913835-30-0
  • Cat. No. CS-0151482
  • Purity ≥97%
  • MDL No. MFCD08235081
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀BClO₃
  • Molecular Weight 200.43
  • Synonym(s) 2-CHLORO-5-ETHOXYBENZENEBORONIC ACID
  • SMILES CCOC1=CC(=C(C=C1)Cl)B(O)O

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering functionalized aryl products with high efficiency. The ethoxy substituent enhances solubility in polar aprotic solvents, while the chloro group enables orthogonal reactivity in sequential transformations. Bench-stable and moisture-tolerant, this reagent streamlines synthesis of complex heterocycles and bioactive intermediates.

Application

(2-Chloro-5-ethoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. Its stability under ambient storage and compatibility with diverse functional groups make it ideal for constructing substituted biaryls and heterocyclic scaffolds in medicinal chemistry and materials synthesis. The chloro and ethoxy substituents provide orthogonal reactivity for downstream modifications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   0.4185
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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