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Structure of 913091-98-2
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6-(Difluoromethyl)nicotinic acid features a strategically positioned difluoromethyl group at the 6-position of the nicotinic acid scaffold, enhancing metabolic stability and modulating electronic properties. This electron-deficient heterocycle integrates readily into bioactive molecules, serving as a key building block for pharmaceuticals targeting kinase pathways and CNS disorders.
6-(Difluoromethyl)nicotinic acid serves as a valuable building block for medicinal chemistry and agrochemical research, enabling the introduction of a lipophilic difluoromethyl group at the C6 position of the pyridine ring. Its stability under standard reaction conditions and compatibility with common coupling protocols facilitate efficient incorporation into diverse heterocyclic scaffolds. The molecule functions as a key intermediate in the synthesis of bioactive compounds where modulated metabolic stability and enhanced membrane permeability are desired.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: