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CS-W001157 4
Total: USD 88.00

(1-Methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol

  • CAS No. 912761-33-2

  • Cat. No. CS-0084127
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1-Methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol|CS-0084127

Structure of 912761-33-2

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General Information

  • CAS No. 912761-33-2
  • Cat. No. CS-0084127
  • Purity ≥95%
  • MDL No. None
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₇N₃O
  • Molecular Weight 195.26
  • Synonym(s) (1-methylimidazol-2-yl)-piperidin-4-ylmethanol
  • SMILES OC(C1=NC=CN1C)C2CCNCC2

Description

This imidazolylpiperidine methanol features a sterically accessible tertiary amine and a hydroxyl-bearing side chain, enabling efficient integration into bioactive scaffolds. The molecule combines moderate lipophilicity with hydrogen-bonding capacity, supporting solubility in common organic solvents and compatibility with diverse coupling reactions.

Application

(1-Methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol serves as a versatile scaffold for medicinal chemistry campaigns, enabling efficient access to imidazole-piperidine hybrids. Its bench-stable nature and orthogonal functionality facilitate downstream derivatization, including amide coupling and alkylation reactions. The molecule functions as a key building block in the synthesis of bioactive heterocycles, particularly those targeting G-protein-coupled receptors and kinase modulators.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   50.08
  • LogP   0.4531
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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