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Structure of 912331-75-0
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7-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole delivers a fluorinated indole scaffold paired with a stable boronate ester for efficient cross-coupling. The tetramethyl-substituted dioxaborolane enhances shelf life and reactivity under standard conditions. This reagent integrates readily into Suzuki-Miyaura transformations, enabling rapid access to functionalized heterocycles in medicinal chemistry and materials synthesis.
7-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables robust coupling with aryl and heteroaryl halides under mild conditions, while the 7-fluoro substituent enhances electrophilic reactivity in downstream transformations. Bench-stable and readily purified by flash chromatography, it facilitates efficient construction of complex indole-based scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: