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CS-W001157 4
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3-Boc-aminomethylazetidine

  • CAS No. 91188-15-7

  • Cat. No. CS-B0427
  • Purity≥95%
  • MDL No.MFCD01861760

*For research and further manufacturing use only, not for direct human use.

3-Boc-aminomethylazetidine|CS-B0427

Structure of 91188-15-7

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General Information

  • CAS No. 91188-15-7
  • Cat. No. CS-B0427
  • Purity ≥95%
  • MDL No. MFCD01861760
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈N₂O₂
  • Molecular Weight 186.26
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCC1CNC1

Description

3-Boc-aminomethylazetidine delivers a sterically constrained azetidine core with a protected amine, enabling direct incorporation into complex scaffolds. The Boc group ensures stability during synthesis and purification, while the aminomethyl handle facilitates downstream functionalization under standard conditions.

Application

3-Boc-aminomethylazetidine serves as a stable, bench-friendly building block for constructing bioactive azetidine-containing scaffolds. The Boc group provides excellent protection of the primary amine, enabling orthogonal functionalization and compatibility with standard coupling reactions. It facilitates efficient incorporation into diverse peptide-like architectures and heterocyclic systems, particularly in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.36
  • LogP   0.7305
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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