tert-Butyl 3,3-difluoropiperidine-1-carboxylate

Name: tert-Butyl 3,3-difluoropiperidine-1-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 911634-75-8
Cat. No. CS-W001679
Purity≥97%
MDL No.MFCD11054112

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 3,3-difluoropiperidine-1-carboxylate|CS-W001679

Structure of 911634-75-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

tert-Butyl 3,3-difluoropiperidine-1-carboxylate is a bench-stable, moisture-tolerant building block featuring a sterically hindered piperidine core with two fluorine atoms at the 3-position. This electron-deficient heterocycle integrates readily into medicinal chemistry campaigns requiring enhanced metabolic stability and modulated basicity.

Application

tert-Butyl 3,3-difluoropiperidine-1-carboxylate serves as a stable, bench-ready building block for the synthesis of fluorinated piperidine scaffolds. The difluoro substitution at the C3 position imparts enhanced metabolic stability and modulates basicity, enabling access to bioactive molecules in medicinal chemistry. Its tert-butyl carbamate group facilitates straightforward deprotection under mild acidic conditions, while the core structure tolerates a range of standard coupling and functionalization reactions, making it a practical choice for iterative synthesis workflows.

General Information

CAS No. 911634-75-8
Cat. No. CS-W001679
Purity ≥97%
MDL No. MFCD11054112
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₇F₂NO₂
Molecular Weight 221.24
Synonym(s) 1-BOC-3,3-DIFLUOROPIPERIDINE
SMILES O=C(N1CCCC(C1)(F)F)OC(C)(C)C

Computational Chemistry Data

TPSA 29.54
LogP 2.6526
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H227-H315-H319
Precautionary Statements : P210-P264-P280-P302+P352-P362+P364-P370+P378-P403-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

911634-75-8 sigma911634-75-8 manufacturer911634-75-8 price911634-75-8 structure911634-75-8 SDSbuy 911634-75-8911634-75-8 supplier911634-75-8 uses911634-75-8 molecular weightprice of 911634-75-8911634-75-8 chemical name formula of 911634-75-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl 3,3-difluoropiperidine-1-carboxylate

CAS No. 911634-75-8

Recommended Products