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Structure of 910553-55-8
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4-Chlorothiophene-2-carbonitrile features a thiophene core with strategically positioned chlorine and nitrile groups, enabling direct incorporation into heterocyclic scaffolds. The electron-deficient thiophene ring facilitates electrophilic substitution, while the nitrile group offers a handle for downstream functionalization. This compound serves as a key building block in pharmaceutical and agrochemical synthesis, particularly in the development of bioactive molecules requiring planar, polarizable frameworks.
4-Chlorothiophene-2-carbonitrile serves as a versatile building block in heterocyclic synthesis, enabling efficient access to functionalized thiophene scaffolds. Its ortho-chloro and nitrile groups provide complementary reactivity for palladium-catalyzed cross-coupling and nucleophilic substitution reactions. The molecule exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H310+H330
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Precautionary Statements : P260-P280-P302+P352
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Lot numbers can be found on the outside label of a product: