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Structure of 91-21-4
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1,2,3,4-Tetrahydroisoquinoline delivers a rigid, electron-rich heterocyclic scaffold ideal for medicinal chemistry. This bench-stable core integrates readily into bioactive molecules, offering enhanced metabolic stability and favorable pharmacokinetic profiles in CNS-targeted drug discovery.
1,2,3,4-Tetrahydroisoquinoline serves as a privileged scaffold in medicinal chemistry, enabling rapid access to bioactive alkaloids and heterocyclic drug candidates. Its nitrogen-rich core exhibits favorable reactivity in Pd-catalyzed couplings, electrophilic substitutions, and reductive amination processes. The compound demonstrates excellent bench stability and compatibility with diverse functional groups, facilitating straightforward derivatization for lead optimization.
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GHS Pictogram :
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GHS No : GHS05,GHS06,GHS08
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Signal Word : Danger
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UN#: 2922
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Class : 8 (6.1)
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Packing Group : Ⅱ
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Hazard Statements : H301-H310-H314-H332-H371-H412
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Precautionary Statements : P260-P261-P262-P264-P270-P271-P273-P280-P301+P330+P331-P302+P352-P304+P340-P330-P361+P364-P363-P405-P501
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Lot numbers can be found on the outside label of a product: