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CS-W001157 4
Total: USD 88.00

1,1-Diphenylmethanamine

  • CAS No. 91-00-9

  • Cat. No. CS-D1366
  • Purity≥97%
  • MDL No.MFCD00008059

*For research and further manufacturing use only, not for direct human use.

1,1-Diphenylmethanamine|CS-D1366

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General Information

  • CAS No. 91-00-9
  • Cat. No. CS-D1366
  • Purity ≥97%
  • MDL No. MFCD00008059
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₃N
  • Molecular Weight 183.25
  • Synonym(s) α-Aminodiphenylmethane
  • SMILES NC(C1=CC=CC=C1)C2=CC=CC=C2

Description

1,1-Diphenylmethanamine offers a sterically hindered primary amine functionality anchored to a diphenylmethyl scaffold. This bench-stable compound integrates readily into amide couplings and reductive amination protocols, serving as a robust building block in synthetic organic chemistry and medicinal chemistry applications.

Application

1,1-Diphenylmethanamine serves as a stable, bench-friendly building block for the synthesis of diarylamine derivatives and pharmaceutically relevant heterocyclic scaffolds. Its tertiary amine functionality enables straightforward alkylation and acylation reactions, while the diphenylmethyl group confers enhanced stability and ease of purification. Functions effectively in standard coupling protocols and is compatible with diverse reaction conditions, making it a practical choice for medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Dong, Li; Aleem, Saadat; Fink, Cynthia A. Tetrahedron Letters, 2010 , vol. 51, # 39 p. 5210 - 5212
  • Route2

    References

    • Hirai, Kunihiro; Katayama, Satoshi; Torii, Takayoshi; Nakaya, Ryotaro; Takahashi, Daisuke Patent: US2013/267697 A1, 2013 ; Location in patent: Page/Page column ;
  • Route3
    • null|null
      22815-70-9
    • ~99%
    • In-stock
      1,1-Diphenylmethanamine|CS-D1366
      91-00-9

    References

    • Widehem, Rodrigue; Lacroix, Thibaut; Bricout, Herve; Monflier, Eric Synlett, 2000 , # 5 p. 722 - 724

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.7347
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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