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CS-W001157 4
Total: USD 88.00

(R)-Ethyl 2-amino-4-phenylbutanoate hydrochloride

  • CAS No. 90940-54-8

  • Cat. No. CS-W014132
  • Molecule weight243.73
  • Purity≥98%
  • MDL No.MFCD03095466

*For research and further manufacturing use only, not for direct human use.

(R)-Ethyl 2-amino-4-phenylbutanoate hydrochloride|CS-W014132

Structure of 90940-54-8

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General Information

  • CAS No. 90940-54-8
  • Cat. No. CS-W014132
  • Purity ≥98%
  • MDL No. MFCD03095466
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₈ClNO₂
  • Molecular Weight 243.73
  • Synonym(s) None
  • SMILES O=C(OCC)[C@H](N)CCC1=CC=CC=C1.[H]Cl

Description

(R)-Ethyl 2-amino-4-phenylbutanoate hydrochloride features a chiral α-amino acid scaffold with a phenyl-substituted aliphatic chain, delivering high enantiomeric purity for asymmetric synthesis. This bench-stable, moisture-tolerant derivative serves as a key building block in peptide analogs and bioactive molecule construction.

Application

(R)-Ethyl 2-amino-4-phenylbutanoate hydrochloride serves as a key chiral building block for the synthesis of biologically relevant heterocycles and amino acid derivatives. Its well-defined stereochemistry enables reliable asymmetric synthesis, while the protected amine and ester functionalities offer orthogonal reactivity for sequential transformations. The hydrochloride salt enhances bench stability and simplifies purification, making it suitable for scalable peptide and medicinal chemistry applications.

Synthesis

  • Route1
    • null|null
      371255-35-5
    • ~89%
    • In-stock
      (R)-Ethyl 2-amino-4-phenylbutanoate hydrochloride|CS-W014132
      90940-54-8

    References

    • Lin, Wen-Qing; He, Ze; Jing, Yi; Cui, Xin; Liu, Hui; Mi, Ai-Qiao Tetrahedron Asymmetry, 2001 , vol. 12, # 11 p. 1583 - 1587
  • Route2
    • 2-(S)-Hydroxy-4-oxo-4-phenylbutyric Acid|CS-0786245
      146912-63-2
    • ~%
    • In-stock
      (R)-Ethyl 2-amino-4-phenylbutanoate hydrochloride|CS-W014132
      90940-54-8

    References

    • Tetrahedron Asymmetry, , vol. 12, # 11 p. 1583 - 1587
  • Route3
    • null|null
      71-43-2
    • ~%
    • In-stock
      (R)-Ethyl 2-amino-4-phenylbutanoate hydrochloride|CS-W014132
      90940-54-8

    References

    • Tetrahedron Asymmetry, , vol. 12, # 11 p. 1583 - 1587

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.9314
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

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