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(1S)-3,3'-Bis[2,4,6-tris(1-methylethyl)phenyl][1,1'-binaphthalene]-2,2'-diol

  • CAS No. 908338-44-3

  • Cat. No. CS-0028347
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1S)-3,3'-Bis[2,4,6-tris(1-methylethyl)phenyl][1,1'-binaphthalene]-2,2'-diol|CS-0028347

Structure of 908338-44-3

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General Information

  • CAS No. 908338-44-3
  • Cat. No. CS-0028347
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅₀H₅₈O₂
  • Molecular Weight 690.99
  • Synonym(s) (1S)-3,3μ-Bis[2,4,6-tris(1-methylethyl)phenyl]-1,1μ-binaphthalene-2,2μ-diol
  • SMILES OC1=C(C2=C3C=CC=CC3=CC(C4=C(C(C)C)C=C(C(C)C)C=C4C(C)C)=C2O)C5=CC=CC=C5C=[C@]1[C@]6=C(C(C)C)C=C(C(C)C)C=C6C(C)C

Application

(1S)-3,3'-Bis[2,4,6-tris(1-methylethyl)phenyl][1,1'-binaphthalene]-2,2'-diol serves as a sterically encumbered, bench-stable chiral ligand for asymmetric catalysis. Its rigid binaphthyl backbone and bulky ortho-tert-butyl groups provide high enantioselectivity in transition metal-catalyzed reactions. The diol functionality enables coordination to metals such as Cu(II), Rh(I), and Pd(II), facilitating efficient asymmetric transformations in synthetic and pharmaceutical applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   15.1456
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   9

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