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CS-W001157 4
Total: USD 88.00

(R)-3,3'-Bis(2,4,6-triisopropylphenyl)-1,1'-bi-2-naphthol

  • CAS No. 247123-09-7

  • Cat. No. CS-0040929
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-3,3'-Bis(2,4,6-triisopropylphenyl)-1,1'-bi-2-naphthol|CS-0040929

Structure of 247123-09-7

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General Information

  • CAS No. 247123-09-7
  • Cat. No. CS-0040929
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅₀H₅₈O₂
  • Molecular Weight 690.99
  • Synonym(s) (S)-3,3'-Bis(2,4,6-triisopropylphenyl)-[1,1'-binaphthalene]-2,2'-diol
  • SMILES OC1=[C@@]([C@@]2=C3C=CC=CC3=C[C@]([C@]4=C(C(C)C)C=C(C(C)C)C=C4C(C)C)=C2O)C5=CC=CC=C5C=C1C6=C(C(C)C)C=C(C(C)C)C=C6C(C)C

Description

(R)-3,3'-Bis(2,4,6-triisopropylphenyl)-1,1'-bi-2-naphthol is a sterically encumbered chiral ligand featuring bulky triisopropylphenyl groups that enhance enantioselectivity in asymmetric catalysis. The rigid biaryl scaffold provides high configurational stability, while the electron-rich naphthol units facilitate metal coordination. This structure enables efficient asymmetric transformations under mild conditions.

Application

(R)-3,3'-Bis(2,4,6-triisopropylphenyl)-1,1'-bi-2-naphthol serves as a sterically encumbered chiral ligand enabling highly enantioselective catalysis in transition-metal-catalyzed transformations. Its robust bis-naphthol framework exhibits excellent bench stability and facilitates efficient asymmetric synthesis of complex molecular architectures. The triisopropylphenyl groups provide exceptional steric shielding, enhancing enantiocontrol in reactions such as allylic alkylation and conjugate addition. Functions reliably across diverse reaction conditions with minimal decomposition.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   15.1456
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   9

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