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Structure of 908269-97-6
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4-Cyclopropylpyridin-2-amine features a cyclopropyl group at the 4-position of a pyridine ring, conferring enhanced lipophilicity and metabolic stability. The primary amine at the 2-position enables straightforward functionalization in synthetic routes. This scaffold integrates readily into bioactive molecules, particularly in kinase inhibitor development and medicinal chemistry campaigns requiring balanced solubility and membrane permeability.
4-Cyclopropylpyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its pyridine nitrogen and primary amine functionality offer orthogonal reactivity for C–N bond formation, while the cyclopropyl group imparts conformational rigidity and enhanced metabolic stability. The compound exhibits excellent bench stability and is compatible with common reaction conditions, facilitating efficient synthesis of kinase inhibitors, GPCR modulators, and other pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: