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CS-W001157 4
Total: USD 88.00

4-Bromo-2-isopropylpyridine

  • CAS No. 908267-63-0

  • Cat. No. CS-0102081
  • Purity≥95%
  • MDL No.MFCD11223217

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-isopropylpyridine|CS-0102081

Structure of 908267-63-0

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General Information

  • CAS No. 908267-63-0
  • Cat. No. CS-0102081
  • Purity ≥95%
  • MDL No. MFCD11223217
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀BrN
  • Molecular Weight 200.08
  • Synonym(s) None
  • SMILES CC(C)C1=NC=CC(Br)=C1

Description

4-Bromo-2-isopropylpyridine features a bromine substituent at the 4-position and an isopropyl group at the 2-position of the pyridine core, creating a sterically hindered, electron-deficient heterocyclic scaffold. This configuration enables selective coupling reactions in medicinal chemistry and materials synthesis, particularly in palladium-catalyzed cross-coupling processes. The molecule exhibits bench-stable handling characteristics under standard conditions.

Application

4-Bromo-2-isopropylpyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined halogen reactivity and ortho-substituted pyridine framework. The isopropyl group provides steric and electronic modulation, enhancing metabolic stability while maintaining compatibility with standard synthetic transformations. Its bench-stable nature and ease of purification make it ideal for constructing complex heterocyclic scaffolds in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.9675
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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