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Structure of 90633-29-7
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1-(2,2,2-Trifluoroethyl)piperidin-4-ol features a trifluoromethylated ethyl linker that enhances lipophilicity and metabolic stability. The piperidinol scaffold provides a polar, hydrogen-bonding handle ideal for medicinal chemistry optimization. This compound integrates readily into bioactive molecules requiring balanced solubility and membrane permeability.
1-(2,2,2-Trifluoroethyl)piperidin-4-ol serves as a versatile building block in medicinal chemistry, enabling the introduction of lipophilic, metabolically stable trifluoromethyl motifs. The piperidin-4-ol core provides a handle for further functionalization, while the trifluoroethyl group enhances membrane permeability and modulates electronic properties. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient synthesis of bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P264-P270-P330
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Lot numbers can be found on the outside label of a product: