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CS-W001157 4
Total: USD 88.00

2-Fluoro-3-methylpyridine-5-boronic acid

  • CAS No. 904326-92-7

  • Cat. No. CS-W003993
  • Purity≥97%
  • MDL No.MFCD03411562

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-3-methylpyridine-5-boronic acid|CS-W003993

Structure of 904326-92-7

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General Information

  • CAS No. 904326-92-7
  • Cat. No. CS-W003993
  • Purity ≥97%
  • MDL No. MFCD03411562
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BFNO₂
  • Molecular Weight 154.94
  • Synonym(s) Boronic acid, B-(6-fluoro-5-methyl-3-pyridinyl)-
  • SMILES OB(c1cnc(c(c1)C)F)O

Description

2-Fluoro-3-methylpyridine-5-boronic acid features a strategically positioned fluorine atom and methyl group that enhance electronic tuning and metabolic stability. This bench-stable boronic acid integrates readily into Suzuki-Miyaura cross-coupling reactions, delivering functionalized heterocycles with high efficiency under standard conditions.

Application

2-Fluoro-3-methylpyridine-5-boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its pyridine framework provides orthogonal reactivity for downstream functionalization, while the boronic acid group offers excellent bench stability and compatibility with diverse functional groups. Ideal for constructing heterocyclic scaffolds in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H318
Precautionary Statements : P280-P305+P351+P338-P310

Quality Control

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   -0.79108
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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