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CS-W001157 4
Total: USD 88.00

6-Hydroxypyridin-3-ylboronic acid

  • CAS No. 903899-13-8

  • Cat. No. CS-W003943
  • Purity≥97%
  • MDL No.MFCD09907979

*For research and further manufacturing use only, not for direct human use.

6-Hydroxypyridin-3-ylboronic acid|CS-W003943

Structure of 903899-13-8

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General Information

  • CAS No. 903899-13-8
  • Cat. No. CS-W003943
  • Purity ≥97%
  • MDL No. MFCD09907979
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆BNO₃
  • Molecular Weight 138.92
  • Synonym(s) None
  • SMILES OB(C1=CC=C(O)N=C1)O

Description

6-Hydroxypyridin-3-ylboronic acid delivers a reactive boronate handle tethered to a pyridinic scaffold, enabling direct incorporation into Suzuki-Miyaura cross-coupling reactions. The hydroxyl group enhances solubility and stabilizes the boronic acid form under standard conditions, facilitating reliable coupling with aryl halides and triflates in aqueous or mixed solvent systems.

Application

6-Hydroxypyridin-3-ylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. The hydroxyl group enhances solubility and facilitates orthogonal functionalization, while the boronic acid moiety offers reliable coupling efficiency under mild conditions. Bench-stable and readily purified by recrystallization, it functions effectively in the synthesis of pharmaceutical intermediates and functional materials.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P341-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   73.32
  • LogP   -1.9453
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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