Lot numbers can be found on the outside label of a product:
4-(4-Formylphenoxy)benzonitrile
-
CAS No. 90178-71-5
- Cat. No. CS-0060258
- Purity≥95%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 90178-71-5
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 90178-71-5
- Cat. No. CS-0060258
- Purity ≥95%
- MDL No. None
- Storage 4°C, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₄H₉NO₂
- Molecular Weight 223.23
- Synonym(s) 4-(4-FORMYLPHENOXY)BENZONITRILE 96
- SMILES C1=C(C=CC(=C1)OC2=CC=C(C=C2)C=O)C#N
Description
4-(4-Formylphenoxy)benzonitrile features a bifunctional architecture combining a reactive aldehyde and a nitrile group, enabling direct conjugation in synthetic workflows. The electron-deficient aromatic core enhances reactivity in nucleophilic addition processes. This compound serves as a modular scaffold for constructing complex heterocycles and functional materials under standard conditions.
Application
4-(4-Formylphenoxy)benzonitrile serves as a versatile bifunctional building block for the synthesis of advanced pharmaceutical intermediates and functional materials. The aldehyde group enables efficient oxime formation, reductive amination, or Suzuki-Miyaura coupling, while the nitrile functions as a handle for hydrolysis to carboxylic acids or reduction to primary amines. Its bench-stable nature and compatibility with diverse reaction conditions facilitate straightforward purification and integration into multi-step synthetic sequences.
Synthesis
-
Route1
-
1194-02-1 -
123-08-0 - ~84%
-
In-stock
90178-71-5
References
-
Li, Bing; Pai, Ramdas; Cardinale, Steven C.; Butler, Michelle M.; Peet, Norton P.; Moir, Donald T.; Bavari, Sina; Bowlin, Terry L. Journal of Medicinal Chemistry, 2010 , vol. 53, # 5 p. 2264 - 2276
-
-
Route2
-
459-57-4 -
767-00-0 - ~88%
-
In-stock
90178-71-5
References
-
MERCK SERONO S.A.; THUNUGUNTLA, Siva Sanjeeva Rao; SUBRAMANYA, Hosahalli; KUNNAM, Satish Reddy; SANIVARU VIJAY, Sekhar Reddy; BINGI, Chakrapani; KUSANUR, Raviraj; SCHWARZ, Matthias; ARLT, Michael Patent: WO2010/115736 A2, 2010 ; Location in patent: Page/Page column 126-127 ; WO 2010/115736 A2
-
-
Route3
-
1194-02-1
-
767-00-0
- ~74%
-
In-stock
90178-71-5
References
-
Dann; Ruff; Wolff; Griessmeier 1984 , vol. 1984, # 3 p. 409 - 425
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 50.09
- LogP 3.16308
- H_Acceptors 3
- H_Donors 0
- Rotatable_Bonds 3
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 4-(4-Formylphenoxy)benzonitrile sigma4-(4-Formylphenoxy)benzonitrile manufacturer4-(4-Formylphenoxy)benzonitrile price4-(4-Formylphenoxy)benzonitrile structure4-(4-Formylphenoxy)benzonitrile SDSbuy 4-(4-Formylphenoxy)benzonitrile4-(4-Formylphenoxy)benzonitrile supplier4-(4-Formylphenoxy)benzonitrile uses4-(4-Formylphenoxy)benzonitrile molecular weightprice of 4-(4-Formylphenoxy)benzonitrile4-(4-Formylphenoxy)benzonitrile chemical name formula of 4-(4-Formylphenoxy)benzonitrile