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CS-W001157 4
Total: USD 88.00

4-(Hydroxymethyl)piperidin-4-ol

  • CAS No. 89584-31-6

  • Cat. No. CS-0053858
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(Hydroxymethyl)piperidin-4-ol|CS-0053858

Structure of 89584-31-6

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General Information

  • CAS No. 89584-31-6
  • Cat. No. CS-0053858
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO₂
  • Molecular Weight 131.17
  • Synonym(s) 4-Hydroxy-4-hydroxyMethylpiperidine
  • SMILES OC1(CO)CCNCC1

Description

4-(Hydroxymethyl)piperidin-4-ol features a piperidinol core with a hydroxymethyl group at the 4-position, enabling dual hydrogen-bonding functionality. This bench-stable scaffold integrates readily into bioactive molecule design, offering enhanced solubility and metabolic stability in medicinal chemistry applications.

Application

4-(Hydroxymethyl)piperidin-4-ol serves as a versatile building block in medicinal chemistry, enabling efficient access to piperidine-based scaffolds through standard functional group manipulations. Its dual hydroxyl and amine functionalities provide orthogonal reactivity for selective derivatization, while the molecule exhibits good bench stability and facilitates purification via standard chromatographic methods. Functions effectively in the synthesis of bioactive heterocycles and drug candidates requiring polar, hydrogen-bonding motifs.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.49
  • LogP   -0.9068
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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