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CS-W001157 4
Total: USD 88.00

4-(1-((tert-Butoxycarbonyl)amino)ethyl)benzoic acid

  • CAS No. 895577-21-6

  • Cat. No. CS-0005268
  • Purity≥97%
  • MDL No.MFCD11505982

*For research and further manufacturing use only, not for direct human use.

4-(1-((tert-Butoxycarbonyl)amino)ethyl)benzoic acid|CS-0005268

Structure of 895577-21-6

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General Information

  • CAS No. 895577-21-6
  • Cat. No. CS-0005268
  • Purity ≥97%
  • MDL No. MFCD11505982
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₉NO₄
  • Molecular Weight None
  • Synonym(s) 4-(1-BOC-AMINO-ETHYL)-BENZOIC ACID
  • SMILES O=C(O)C1=CC=C(C(NC(OC(C)(C)C)=O)C)C=C1

Description

This protected amino acid derivative features a para-substituted benzoic acid scaffold linked via a flexible ethyl spacer to a tert-butoxycarbonyl-protected amine. The Boc group provides stability under standard conditions, enabling straightforward deprotection during peptide synthesis workflows.

Application

4-(1-((tert-Butoxycarbonyl)amino)ethyl)benzoic acid serves as a versatile building block for peptide and heterocyclic synthesis, enabling efficient introduction of both carboxylic acid and protected amine functionalities. The tert-butyl carbamate group offers excellent stability under basic conditions and mild deprotection with trifluoroacetic acid, facilitating sequential functionalization. Its benzoic acid moiety supports derivatization via standard coupling reactions, while the alkyl linker provides conformational flexibility for medicinal chemistry applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.9705
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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