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Structure of 895243-39-7
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trans-1-Benzyl-4-(ethoxycarbonyl)pyrrolidine-3-carboxylic acid features a rigid trans-pyrrolidine core with orthogonal functional handles: a benzyl group for steric and electronic modulation, and an ethoxycarbonyl moiety enabling further derivatization. This configuration enhances conformational stability and solubility in organic solvents, facilitating use in peptide synthesis and medicinal chemistry scaffolds.
trans-1-Benzyl-4-(ethoxycarbonyl)pyrrolidine-3-carboxylic acid serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to pyrrolidine-based scaffolds prevalent in bioactive molecules. Its well-defined stereochemistry and orthogonal functional groups—namely the benzylic handle, ester, and carboxylic acid—facilitate selective transformations, including hydrogenation, amidation, and ring modification. The compound exhibits excellent bench stability and simplifies purification in multi-step syntheses, making it a reliable component in API precursor development and target-oriented synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: