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Structure of 32829-25-7
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2-(1H-indazol-1-yl)acetic acid features a rigid indazole core linked via a methylene bridge to a carboxylic acid group, enabling direct integration into bioactive molecules. The electron-rich indazole moiety enhances π-stacking interactions in target binding pockets, while the pendant acid facilitates conjugation or salt formation for improved solubility and pharmacokinetic tuning.
2-(1H-indazol-1-yl)acetic acid serves as a versatile building block for the synthesis of indazole-containing bioactive molecules, enabling direct conjugation to amine-functionalized scaffolds via amide bond formation. Its bench-stable carboxylic acid group exhibits excellent functional group tolerance and facilitates straightforward purification, making it well-suited for medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: