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CS-W001157 4
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(1S,2S)-N1,N1-Dimethylcyclohexane-1,2-diamine

  • CAS No. 894493-95-9

  • Cat. No. CS-W018664
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1S,2S)-N1,N1-Dimethylcyclohexane-1,2-diamine|CS-W018664

Structure of 894493-95-9

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General Information

  • CAS No. 894493-95-9
  • Cat. No. CS-W018664
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₈N₂
  • Molecular Weight 142.24
  • Synonym(s) N,N'-Dimethyl-1S,2S-Diaminocyclohexane
  • SMILES N[C@@H]1[C@@H](N(C)C)CCCC1

Description

This chiral diamine features a rigid cyclohexane backbone with stereodefined (1S,2S) configuration, enabling precise control in asymmetric synthesis. The N1,N1-dimethyl substitution enhances solubility and steric shielding, while the secondary amine sites facilitate coordination in catalytic systems. Ideal for ligand design and enantioselective transformations.

Application

(1S,2S)-N1,N1-Dimethylcyclohexane-1,2-diamine serves as a chiral diamine scaffold in asymmetric synthesis, enabling stereoselective catalysis through well-defined coordination to transition metals. Its bench-stable, crystalline form facilitates handling and purification, while the N1,N1-dimethyl substitution enhances solubility and resistance to oxidation. Functions effectively in enantioselective hydrogenation, C–C coupling, and metal-ligand complex formation, offering broad compatibility with common reaction conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314-H318
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.26
  • LogP   0.8179
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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