Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

N-((1R,2R)-2-Aminocyclohexyl)-4-methylbenzenesulfonamide

  • CAS No. 174291-96-4

  • Cat. No. CS-0093711
  • Molecule weight268.38
  • Purity≥97%
  • MDL No.MFCD09842716

*For research and further manufacturing use only, not for direct human use.

N-((1R,2R)-2-Aminocyclohexyl)-4-methylbenzenesulfonamide|CS-0093711

Structure of 174291-96-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 174291-96-4
  • Cat. No. CS-0093711
  • Purity ≥97%
  • MDL No. MFCD09842716
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₀N₂O₂S
  • Molecular Weight 268.38
  • Synonym(s) (1R,2R)-(-)-N-p-Tosyl-1,2-cyclohexanediamine
  • SMILES N[C@@H]1CCCC[C@H]1NS(C2=CC=C(C)C=C2)(=O)=O

Description

N-((1R,2R)-2-Aminocyclohexyl)-4-methylbenzenesulfonamide features a chiral cyclohexylamine scaffold paired with a para-methylbenzenesulfonamide group, delivering enhanced solubility and metabolic stability. This configuration supports precise stereochemical control in medicinal chemistry applications, enabling efficient incorporation into targeted small-molecule libraries.

Application

N-((1R,2R)-2-Aminocyclohexyl)-4-methylbenzenesulfonamide serves as a versatile chiral sulfonamide building block for medicinal chemistry and catalyst design. Its (1R,2R)-cyclohexylamine core provides defined stereochemistry, while the para-methylbenzenesulfonamide group offers excellent solubility and stability. The molecule facilitates amide coupling reactions and functions as a scaffold in the synthesis of kinase inhibitors and other bioactive compounds.

Synthesis

  • Route1

    References

    • Li, Guigen; Chang, Han-Ting; Sharpless, K. Barry Angewandte Chemie, 1996 ,  vol. 108,  # 4  p. 449 - 452

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   72.19
  • LogP   1.54322
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 174291-96-4 sigma174291-96-4 manufacturer174291-96-4 price174291-96-4 structure174291-96-4 SDSbuy 174291-96-4174291-96-4 supplier174291-96-4 uses174291-96-4 molecular weightprice of 174291-96-4174291-96-4 chemical name formula of 174291-96-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label