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Structure of 893738-23-3
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5-Cyclopropylpyridine-3-carboxylic acid features a cyclopropyl group at the 5-position of a pyridine ring, enhancing lipophilicity and metabolic stability. The carboxylic acid moiety enables direct conjugation or salt formation, facilitating solubility control. This scaffold integrates readily into bioactive molecules, particularly in kinase inhibitors and CNS-targeted pharmaceuticals, where its rigid, electron-deficient core supports target binding.
5-Cyclopropylpyridine-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its pyridine core provides favorable electronic properties for target binding, while the cyclopropyl group enhances metabolic stability and modulates lipophilicity. The carboxylic acid functionality facilitates direct coupling reactions or derivatization, offering broad utility in peptide conjugation, prodrug design, and transition metal-catalyzed transformations. Bench-stable and readily purified by recrystallization, it functions effectively in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: