Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Methyl-1H-pyrazole-4-carboxamide

  • CAS No. 89280-01-3

  • Cat. No. CS-0199258
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Methyl-1H-pyrazole-4-carboxamide|CS-0199258

Structure of 89280-01-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 89280-01-3
  • Cat. No. CS-0199258
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇N₃O
  • Molecular Weight 125.13
  • Synonym(s) None
  • SMILES CN1C=C(C(N)=O)C=N1

Description

1-Methyl-1H-pyrazole-4-carboxamide features a pyrazole core with a methylated nitrogen and carboxamide functionality, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibition and receptor modulation, offering robust performance under standard bench conditions.

Application

1-Methyl-1H-pyrazole-4-carboxamide serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to pyrazole-based scaffolds. Its amide functionality supports diverse coupling reactions, while the methyl group enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability, facilitates straightforward purification, and demonstrates broad compatibility with standard synthetic transformations, making it a practical choice for lead optimization and API intermediate synthesis.

Synthesis

  • Route1

    References

    • Jachak, Madhukar N.; Ghagare, Maruti G.; Birari, Dilip R.; Rote, Ramhari V.; Kazi, Muddassar A.; Jachak, Sanjay M.; Toche, Raghunath B. Monatshefte fur Chemie, 2010 , vol. 141, # 5 p. 569 - 576

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   60.91
  • LogP   -0.481
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-Methyl-1H-pyrazole-4-carboxamide sigma1-Methyl-1H-pyrazole-4-carboxamide manufacturer1-Methyl-1H-pyrazole-4-carboxamide price1-Methyl-1H-pyrazole-4-carboxamide structure1-Methyl-1H-pyrazole-4-carboxamide SDSbuy 1-Methyl-1H-pyrazole-4-carboxamide1-Methyl-1H-pyrazole-4-carboxamide supplier1-Methyl-1H-pyrazole-4-carboxamide uses1-Methyl-1H-pyrazole-4-carboxamide molecular weightprice of 1-Methyl-1H-pyrazole-4-carboxamide1-Methyl-1H-pyrazole-4-carboxamide chemical name formula of 1-Methyl-1H-pyrazole-4-carboxamide
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label