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CS-W001157 4
Total: USD 88.00

1-Methyl-1H-pyrazole-4-carboxaldehyde

  • CAS No. 25016-11-9

  • Cat. No. CS-W019871
  • Purity≥96%
  • MDL No.MFCD00460465

*For research and further manufacturing use only, not for direct human use.

1-Methyl-1H-pyrazole-4-carboxaldehyde|CS-W019871

Structure of 25016-11-9

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General Information

  • CAS No. 25016-11-9
  • Cat. No. CS-W019871
  • Purity ≥96%
  • MDL No. MFCD00460465
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆N₂O
  • Molecular Weight 110.11
  • Synonym(s) None
  • SMILES O=CC1=CN(C)N=C1

Description

(S)-4-Benzyloxycarbonylamino-2-(Fmoc-amino)butyric acid a substituted fluorene compound for proteomics research. Also used in agrochemical, pharmaceutical and dyestuff field.

Application

1-Methyl-1H-pyrazole-4-carboxaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrazole-based scaffolds through standard aldehyde functionalization. Its reactivity facilitates imine formation, reductive amination, and coupling reactions with amines and hydrazines, while the methyl group enhances stability and simplifies purification. This compound functions effectively in multistep synthesis and is compatible with common bench-scale protocols.

Synthesis

  • Route1
    • null|null
      930-36-9
    • null|null
      68-12-2
    • ~78%
    • In-stock
      1-Methyl-1H-pyrazole-4-carboxaldehyde|CS-W019871
      25016-11-9

    References

    • WO2008/144767 A1, ; Page/Page column 117 ; WO 2008/144767 A1
  • Route2
    • null|null
      930-36-9
    • ~%
    • In-stock
      1-Methyl-1H-pyrazole-4-carboxaldehyde|CS-W019871
      25016-11-9

    References

    • WO2014/2109 A1, ; Page/Page column 131 ;
  • Route3
    • null|null
      18655-47-5
    • null|null
      60-34-4
    • ~95%
    • In-stock
      1-Methyl-1H-pyrazole-4-carboxaldehyde|CS-W019871
      25016-11-9

    References

    • Bulletin de la Societe Chimique de France, , # 5 p. 660 - 666

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H317-H318-H335
Precautionary Statements : P261-P264-P271-P272-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   34.89
  • LogP   0.2326
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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