6-Methoxypyridazin-4-amine

Name: 6-Methoxypyridazin-4-amine
Brand: ChemScene
Availability: InStock
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CAS No. 89179-64-6
Cat. No. CS-0458624
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 89179-64-6

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Description

6-Methoxypyridazin-4-amine features a pyridazinone core with a methoxy group at the 6-position and an amine at the 4-position, delivering enhanced solubility and stability. This scaffold integrates readily into bioactive molecules, serving as a key building block for kinase inhibitors and pharmaceutical intermediates.

Application

6-Methoxypyridazin-4-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to heterocyclic scaffolds through nucleophilic substitution and coupling reactions. Its pyridazinone core exhibits favorable bench stability and compatibility with common functional groups, facilitating straightforward derivatization for API development. The methoxy and amine functionalities provide orthogonal handles for further modification, enhancing synthetic flexibility in lead optimization campaigns.

General Information

CAS No. 89179-64-6
Cat. No. CS-0458624
Purity ≥95%
MDL No. None
Storage -20°C, sealed storage, away from moisture and light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₇N₃O
Molecular Weight 125.13
Synonym(s) None
SMILES COC1=NN=CC(N)=C1

Computational Chemistry Data

TPSA 61.03
LogP 0.0674
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridazine compounds

Key Words

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6-Methoxypyridazin-4-amine

CAS No. 89179-64-6

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