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tert-Butyl (8-aminooctyl)carbamate

  • CAS No. 88829-82-7

  • Cat. No. CS-0032884
  • Purity≥96%
  • MDL No.MFCD02094499

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (8-aminooctyl)carbamate|CS-0032884

Structure of 88829-82-7

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General Information

  • CAS No. 88829-82-7
  • Cat. No. CS-0032884
  • Purity ≥96%
  • MDL No. MFCD02094499
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₈N₂O₂
  • Molecular Weight 244.37
  • Synonym(s) 1-Boc-1,8-diaminooctane
  • SMILES NCCCCCCCCNC(OC(C)(C)C)=O

Description

tert-Butyl (8-aminooctyl)carbamate delivers a protected amine handle for conjugation and functionalization workflows. This bench-stable, moisture-tolerant derivative features a long aliphatic chain that enhances solubility in organic media while enabling efficient deprotection under mild acidic conditions.

Application

tert-Butyl (8-aminooctyl)carbamate serves as a versatile protecting group for primary amines, enabling selective functionalization in complex molecule synthesis. Its tert-butyl carbamate moiety provides excellent bench stability and facilitates easy removal under mild acidic conditions. The aliphatic chain supports compatibility with diverse coupling reactions and offers flexibility in the construction of long-chain amine-containing scaffolds relevant to medicinal chemistry and polymer science.

Synthesis

  • Route1

    References

    • Cinelli, Maris A.; Cordero, Brenda; Dexheimer, Thomas S.; Pommier, Yves; Cushman, Mark Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 20 p. 7145 - 7155
  • Route2
    • null|null
      556065-56-6
    • ~99%
    • In-stock
      tert-Butyl (8-aminooctyl)carbamate|CS-0032884
      88829-82-7

    References

    • Fixon-Owoo, Solomon; Levasseur, Frederic; Williams, Keith; Sabado, Thomas N.; Lowe, Mike; Klose, Markus; Mercier, A. Joffre; Fields, Paul; Atkinson, Jeffrey Phytochemistry, 2003 , vol. 63, # 3 p. 315 - 334
  • Route3

    References

    • Tang, Wei; Fang, Shiyue Tetrahedron Letters, 2008 , vol. 49, # 41 p. 6003 - 6006

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   2.8104
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   8

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