Lot numbers can be found on the outside label of a product:
2-(2-Chloropyridin-4-yl)acetic acid
-
CAS No. 887580-55-4
- Cat. No. CS-0060700
- Purity≥97%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 887580-55-4
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 887580-55-4
- Cat. No. CS-0060700
- Purity ≥97%
- MDL No. None
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₇H₆ClNO₂
- Molecular Weight 171.58
- Synonym(s) 2-Chloropyridine-4-acetic acid
- SMILES O=C(O)CC1=CC(Cl)=NC=C1
Description
This acetic acid derivative features a 2-chloropyridin-4-yl group that enhances electron-withdrawing character and facilitates coupling reactions. The pendant carboxylic acid enables direct conjugation to amine-functionalized substrates, supporting efficient synthesis of bioactive compounds in medicinal chemistry workflows.
Application
2-(2-Chloropyridin-4-yl)acetic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-containing scaffolds through standard functional group transformations. Its chlorine substituent facilitates palladium-catalyzed cross-coupling reactions, while the carboxylic acid group supports direct amidation or esterification. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for scalable synthesis and process development.
Synthesis
-
Route1
-
896107-40-7 - ~57%
-
In-stock
887580-55-4
References
-
Zeitlmann, Lutz; Niestroj, Andre; Heiser, Ulrich Patent: US2011/224225 A1, 2011 ; Location in patent: Page/Page column 31 ; US 20110224225 A1
-
-
Route2
-
In-stock
937236-73-2 - ~%
-
In-stock
887580-55-4
References
-
NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD.; BURNS, Christopher, J.; GOSWAMI, Rajesh; JACKSON, Randy, W.; LESSEN, Thomas; LI, Weiping; PEVEAR, Daniel; TIRUNAHARI, Pavan, Kumar; XU, Hongyu Patent: WO2010/130708 A1, 2010 ; Location in patent: Page/Page column 107 ; WO 2010/130708 A1
-
-
Route3
-
In-stock
3678-62-4 - ~%
-
In-stock
887580-55-4
References
-
Zeitlmann, Lutz; Niestroj, Andre; Heiser, Ulrich Patent: US2011/224225 A1, 2011 ; US 20110224225 A1
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 50.19
- LogP 1.3621
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2-(2-Chloropyridin-4-yl)acetic acid sigma2-(2-Chloropyridin-4-yl)acetic acid manufacturer2-(2-Chloropyridin-4-yl)acetic acid price2-(2-Chloropyridin-4-yl)acetic acid structure2-(2-Chloropyridin-4-yl)acetic acid SDSbuy 2-(2-Chloropyridin-4-yl)acetic acid2-(2-Chloropyridin-4-yl)acetic acid supplier2-(2-Chloropyridin-4-yl)acetic acid uses2-(2-Chloropyridin-4-yl)acetic acid molecular weightprice of 2-(2-Chloropyridin-4-yl)acetic acid2-(2-Chloropyridin-4-yl)acetic acid chemical name formula of 2-(2-Chloropyridin-4-yl)acetic acid