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CS-W001157 4
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2-Chlorophenylglycine

  • CAS No. 88744-36-9

  • Cat. No. CS-W002235
  • Purity≥98%
  • MDL No.MFCD00049324

*For research and further manufacturing use only, not for direct human use.

2-Chlorophenylglycine|CS-W002235

Structure of 88744-36-9

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General Information

  • CAS No. 88744-36-9
  • Cat. No. CS-W002235
  • Purity ≥98%
  • MDL No. MFCD00049324
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈ClNO₂
  • Molecular Weight 185.61
  • Synonym(s) None
  • SMILES ClC1=CC=CC=C1C(N)C(O)=O

Description

2-Chlorophenylglycine serves as a key chiral building block in medicinal chemistry, featuring a chlorinated phenyl ring that enhances metabolic stability and modulates electronic properties. This amino acid derivative integrates readily into peptide scaffolds and supports the synthesis of bioactive compounds with targeted pharmacological profiles.

Application

2-Chlorophenylglycine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide-like scaffolds. Its ortho-chloro substitution enhances metabolic stability and modulates electronic properties, while the amino acid backbone supports straightforward derivatization via standard coupling and protection strategies. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for both academic research and industrial process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.4244
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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