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CS-W001157 4
Total: USD 88.00

1-Methyl-2-phenyl-1H-indole

  • CAS No. 3558-24-5

  • Cat. No. CS-W015261
  • Purity≥98%
  • MDL No.MFCD00022892

*For research and further manufacturing use only, not for direct human use.

1-Methyl-2-phenyl-1H-indole|CS-W015261

Structure of 3558-24-5

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General Information

  • CAS No. 3558-24-5
  • Cat. No. CS-W015261
  • Purity ≥98%
  • MDL No. MFCD00022892
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₃N
  • Molecular Weight 207.28
  • Synonym(s) N-Methyl-2-phenyl indole
  • SMILES CN1C(=CC2=C1C=CC=C2)C1=CC=CC=C1

Description

Reaction of 1-methyl-2-phenylindole with nitrogen dioxide or with nitrous acid (NaNO2-CH3COOH) in benzene has been studied. 1-Methyl-2-phenylindole is reported to react with malondialdehyde (MDA) and 4-hydroxyalkenals to afford a stable chromophore with intense maximal absorbance at 586nm.1-Methyl-2-phenylindole may be used in the following studies:The estimation of lipid peroxidation in third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ)Bg.As chromogenic agent for the determination of estimation of malondialdehyde (MDA) production.Colorimetric assay of lipid peroxidation.Synthesis of 1-methyl-2-phenyl-3-(1,3,4-thiadiazol-2-yldiazenyl)-1H-indole.Synthesis of 3-(5-ethyl-1,3,4-thiadiazol-2-yldiazenyl)-1-methyl-2-phenyl-1H-indole.

Synthesis

  • Route1
    • In-stock
      1-Bromo-2-(phenylethynyl)benzene|CS-0333622
      21375-88-2
    • null|null
      74-89-5
    • ~97%
    • In-stock
      1-Methyl-2-phenyl-1H-indole|CS-W015261
      3558-24-5

    References

    • DALHOUSIE UNIVERSITY; STRADIOTTO, Mark John Patent: WO2013/159229 A1, 2013 ; Location in patent: Paragraph 00206-00208 ;
  • Route2

    References

    • Yang, Shang-Dong; Sun, Chang-Liang; Fang, Zhao; Li, Bi-Jie; Li, Yi-Zhou; Shi, Zhang-Jie Angewandte Chemie - International Edition, 2008 , vol. 47, # 8 p. 1473 - 1476
  • Route3
    • null|null
      128746-62-3
    • In-stock
      Phenylboronic acid|CS-W001090
      98-80-6
    • ~99%
    • In-stock
      1-Methyl-2-phenyl-1H-indole|CS-W015261
      3558-24-5

    References

    • Ibad, Muhammad Farooq; Zinad, Dhafer Saber; Hussain, Munawar; Ali, Asad; Villinger, Alexander; Langer, Peter Tetrahedron, 2013 , vol. 69, # 35 p. 7492 - 7504

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   4.93
  • LogP   3.8453
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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