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CS-W001157 4
Total: USD 88.00

(E)-Methyl 3-(4-(bromomethyl)phenyl)acrylate

  • CAS No. 88738-86-7

  • Cat. No. CS-0886877
  • Molecule weight255.11
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(E)-Methyl 3-(4-(bromomethyl)phenyl)acrylate|CS-0886877

Structure of 88738-86-7

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General Information

  • CAS No. 88738-86-7
  • Cat. No. CS-0886877
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁BrO₂
  • Molecular Weight 255.11
  • Synonym(s) None
  • SMILES O=C(OC)/C=C/C1=CC=C(CBr)C=C1

Description

(E)-Methyl 3-(4-(bromomethyl)phenyl)acrylate features a conjugated enoate system paired with a reactive bromomethyl handle, enabling efficient coupling in cross-coupling and functionalization workflows. The (E)-configuration ensures geometric stability, while the ester group enhances solubility and compatibility with transition metal catalysis under standard conditions.

Application

(E)-Methyl 3-(4-(bromomethyl)phenyl)acrylate serves as a versatile synthetic building block for the construction of biaryl and styryl derivatives. The bromomethyl group enables efficient Suzuki-Miyaura and Sonogashira coupling reactions, while the conjugated acrylate moiety supports Michael additions and Diels-Alder transformations. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for iterative synthesis in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P362+P364

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.7677
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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